Mechanism of Action of Insulin 


Insulin is a hormone produced by the pancreas that plays a crucial role in regulating blood glucose levels. 

Here’s how it works:

Glucose Absorption: When carbohydrates are consumed, body breaks them down into glucose, a simple sugar that serves as a vital energy source. 

(a) Insulin attaches to insulin receptors of the target cell.
(b) Activates a cascade of signaling leading to the formation of certain protein called GLUT4 which is a glucose transporter protein, 
(c) GLUT4 is then translocated to the Plasma membrane and Transport glucose into the cell.
(d) Inside the cell Glucose converted to Glucose-6-phosphate which is used as a source of energy. 
- In that way the glucose absorption pathway is regulated by the action of Insulin. 


 FIG: MOA of insulin 

Picture Source: https://www.researchgate.net/figure/Mechanism-of-action-of-insulin-17_fig1_325007874

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